Pharmaceutical Applications

A range of bioactive compounds can be mixed with the organogel base formulations including proteins, nucleic acids (DNA, RNA, RNAi, plasmids, virus particles), polysaccharides, and plant phytochemicals.

Organogels provide the ideal environment for providing active pharmaceutical ingredients (API) allowing novel combinations of compounds to be formulated. All organogels contain regulatory approved excipients that remain unmodified during our gelation process. There are no regulatory issues and as product can be produced using cGMP under sterile conditions it is safe to use with a long shelf life.

The absence of water provides an ideal stable environment for the API.

A range of both oral and topical organogels are available with ideal characteristics for drug delivery.

Therapeutic delivery of proteins through the skin show potential due to the enhanced penetration of proteins observed which is protein / peptide specific.

API concentrations range considerably and the organogels are able to tolerate additives that either enhance gelation or decrease gelation using methods devised based around donor and receptor groups present in added API compounds. The gelling agent can either be increased or decreased to obtain the desired gel properties. The gels are tuneable based on an application's requirements.